Compostos bioativos e modulação intestinal na ansiedade : uma revisão integrativa

Abstract

Cases of anxiety have increased in recent decades and anxiety, although natural, is considered pathological when it compromises the normal functioning of the body. Communication between the intestine and the central nervous system is essential for the body's homeostasis and response to stress. The modulation of the intestinal microbiota and the use of bioactive compounds can be strategies in the treatment of anxiety, given the relevance of this condition in modern society and the limitations of traditional medicines and their impacts on quality of life, food appears as a potential ally. This review aims to identify the relationship between bioactive compounds and intestinal modulation in anxiety conditions, through an integrative review. For the bibliographic review, articles were selected from the Pubmed database, with publications from the last ten years. The inclusion criteria were defined as follows: research carried out in the last 10 (ten) years, in Portuguese and English, indexed in the PubMed database. Studies show that bioactive compounds can promote the proliferation of beneficial bacteria and the production of important metabolites, which play a role in regulating anxiety symptoms. However, it is important to recognize that many of these studies were conducted in animal models, and the evidence in humans is still limited and sometimes inconsistent, necessitating further studies in this area.