Utilização da Cannabis no tratamento da Síndrome de West

Abstract

Cannabis sativa, a species among many existing and known as marijuanas, hasbeen used for therapeutic purposes since the beginning of time. In its composition, it is possibleto find several active ingredients, among them, Cannabidiol (CBD) and D9-tetrahydrocannabidiol (THC) stand out. Cannabis, little by little is taking space in the treatmentof different diseases, among them, epilepsy. According to the Ministry of Health (2015), epilepsy is a temporary and reversible change in the functioning of the brain, which has not been caused by fever, drugs or metabolic disorders and is expressed by repeated epileptic seizures. West Syndrome (SW) is a rare type of severe childhood epilepsy syndrome, and themost commonly used therapies are hormone therapy, medication or surgical intervention. Based on these therapies, the Federal Council of Medicine, through Resolution No. 2,113 / 2014, approves the compassionate use of cannabidiol for the treatment of child and adolescentepilepsies refractory to conventional treatments. For the elaboration of this integrative review,the databases, Scielo, Lilacs and PubMed were used, the inclusion parameters were articles published in the last 5 years, in Portuguese, English and Spanish, with full text. Given the information gathered, it was possible to identify that Cannabis has become a potential therapeutic route for the treatment and control of epileptic conditions that no longer respond toconventional treatments, so it is necessary to carry out further experimental studies that can prove the effectiveness of the effects of this plant.